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If you are upgrading Exchange Server from an unsupported CU to the current CU and no intermediate CUs are available, you should first upgrade to the latest version of .NET that's supported by your version of Exchange Server and then immediately upgrade to the current CU. This method doesn't replace the need to keep your Exchange servers up to date and on the latest supported CU. Microsoft makes no claim that an upgrade failure will not occur using this method, which may result in the need to contact Microsoft Support Services.
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