Introduction Silicon is beneficial for many plants for growth, yield and enhancing resistance to biotic and abiotic stresses. In the present study, silicon as a form of rice hull sand mixture (3:2 v/v) was used in simplified hydroponic system to evaluate the performance and disease resistance of Capsicum annuum L. The nutrients were supplied by NF (New Formula) or Albert’s solution. Results Continuous monitoring of soluble silicon content in the simplified hydroponic boxes revealed that a high amount of silicon was leached by the rice hull sand medium. Disease resistance was assessed by challenge inoculation of harvested fruits with anthracnose-causing fungi, Colletotrichum gloeosporioides, and it was observed a significant disease reduction (over 83 %) in fruits harvested from simplified hydroponic system compared to that of liquid hydroponic system. Shoot length, root length, fruit length, fruit weight and fruit firmness were also increased significantly in simplified system compared to the liquid system. However…